Dr. Zauderer received the Career Development Award for her current research project involving the role of the BAP 1 gene (BRCA associated protein-1) in mesothelioma. Inherited mutations in the BAP1 gene have been shown to predispose patients to malignant pleural mesothelioma. “A better understanding of this gene could mean a better understanding of mesothelioma and how it develops in patients,” Zauderer states.
Dr. Zauderer began working on this project three years ago and has been gathering specimens and samples throughout this time. She predicts that enough samples will be collected within the next year or two to begin analysis that could yield significant insights and statistics. Her goal in 3 to 5 years is to have a plausible drug that has already completed phase 1 testing or is ready to begin phase 1 testing in clinical trials.
In an interview, Dr. Zauderer expressed her passion for her work, citing her many college application essays that she recently came across. “All my applications were about how I wanted to use genetics to help medicine. 20 years later, that’s actually what I do,” Zauderer states.
The Career Development Award provides funding from the Department of Defense to support a specific research project. Funding is provided to the selected project over a three year period, during which certain research components must be met and specific goals achieved. Mesothelioma is a disease of interest to the Department of Defense, as an estimated one third of mesothelioma patients either served in the Navy or worked in shipyards.